HTX-019 via 2-min injection or 30-min infusion in healthy subjects
نویسندگان
چکیده
منابع مشابه
Comparison of the pharmacokinetics, safety and tolerability of daptomycin in healthy adult volunteers following intravenous administration by 30 min infusion or 2 min injection
OBJECTIVES Two randomized Phase I studies in separate populations of healthy adult volunteers investigated the pharmacokinetics, safety and tolerability of daptomycin (Cubicin; Novartis Pharma AG, Basel, Switzerland) administered as a 2 min intravenous (iv) injection, relative to the currently licensed 30 min iv infusion. METHODS Study 1 was an open-label, single-dose, two-period, crossover s...
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Introduction Fosaprepitant, an intravenous (IV) aprepitant prodrug for chemotherapy-induced nausea and vomiting prophylaxis, is associated with systemic and infusion-site reactions attributed in part to its surfactant, polysorbate 80. HTX-019 is an IV aprepitant formulation free of polysorbate 80 and other synthetic surfactants. Materials and methods This open-label, single-dose, randomized, ...
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ژورنال
عنوان ژورنال: Future Oncology
سال: 2019
ISSN: 1479-6694,1744-8301
DOI: 10.2217/fon-2018-0809